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Articles by Indian Institute of Technology

Recent approach to incorporate tellurium in metal carbonyl cluster utilizing extrusion reaction

Published on: 26th November, 2019

OCLC Number/Unique Identifier: 9269425535

The incorporation of tellurium into metal carbonyl using tellurium transfer/ extrusion reaction is presented in this work. The results bring one of the new ways to incorporate tellurium by transferring it from one molecule to another molecule, in comparison to the work so far where either insertion or extrusion reactions were shown. The reactions of PhC2TeC2Ph with the metal carbonyl cluster produced thermodynamically stable metal carbonyl tellurium clusters.
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Quantification of minor, trace and toxic elements in stems of Santalum album (L.), Mangiferra indica (L.) and Tinospora cordifolia by instrumental neutron activation analysis

Published on: 4th March, 2022

OCLC Number/Unique Identifier: 9437625422

Stems of Santalum album (Sandalwood), Mangiferra indica (Mango wood), and Tinospora cordifolia (Giloy) are widely used in the preparation of herbal medicines and formulations in the traditional Indian health care system called Ayurveda. These were analyzed for 4 minor (K, Ca, Cl, Mg) and 13 traces (As, Ce, Co, Cr, Cu, Fe, Hg, La, Mn, Na, Se, V, and Zn) including toxic elements by instrumental neutron activation analysis (INAA). Samples in powder form along with reference materials (NIST SRM 1547 and INCT MPH-2) as comparators were irradiated for 1 min/6 h in Dhruva/CIRUS reactors at BARC, Mumbai. Gamma activity was measured by high-resolution gamma-ray spectrometry. In general, K, Ca, Fe, Mn, and Zn contents are very high in all the samples but Santalum album, widely used as a perfume, is more enriched in K, Ca, Cr, Zn, and Se. The concentration of Ca is always high as a major constituent (> 10 mg/g) in all the stem/bark of plant species. A strong inverse correlation (R2 = 0.9999) was observed between Fe and Zn in all three samples and that may be useful in drug manufacturing.
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In the pursuit of a new route on acute myeloid leukemia treatment

Published on: 29th December, 2021

Acute myeloid leukaemia (AML) is the forefront disorder of the bone marrow among others that disrupt the normal production of blood cells and platelets. The bone marrow microenvironment or the bone marrow niche (BM niche) that orchestrates the proliferation and survival of Leukaemic stem cells (LSC) is the reason for relapse after complete remission and also chemotherapy drug resistance. As for most cancers oxidative phosphorylation, a fundamental mitochondrial process of energy production, is under focus for the treatment of AML and a novel strategy of targeting heat shock proteins appears as a promising route for further research.
Cite this ArticleCrossMarkPublonsHarvard Library HOLLISGrowKudosResearchGateBase SearchOAI PMHAcademic MicrosoftScilitSemantic ScholarUniversite de ParisUW LibrariesSJSU King LibrarySJSU King LibraryNUS LibraryMcGillDET KGL BIBLiOTEKJCU DiscoveryUniversidad De LimaWorldCatVU on WorldCat
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